Highlights of recent faculty research.

Rare coding variants in 35 genes associate with circulating lipid levels-A multi-ancestry analysis of 170,000 exomes

Hindy G, Dornbos P, Chaffin MD, … Bielak LF, Bis JC, Blangero J, … Bown MJ, Brody JA, Broome JG, … Lehman DM, Lemaitre RN, Linneberg A, … Preuss M, Psaty BM, Qi Q, … Flannick JA, Khera AV, Peloso GM. Am J Hum Genet. 2021 Dec 16:S0002-9297(21)00452-3. doi: 10.1016/j.ajhg.2021.11.021. Online ahead of print. PMID: 34932938.

The power of genetic diversity in genome-wide association studies of lipids

Graham SE, Clarke SL, Wu KH, … Christensen H, Brody JA, Feitosa MF, … Thiery J, Bis JC, Nadkarni GN, … Province MA, Psaty BM, Brandslund I, … Deloukas P, Sun YV, Willer CJ. Nature. 2021 Dec;600(7890):675-679. doi: 10.1038/s41586-021-04064-3. Epub 2021 Dec 9. PMID: 34887591.

The power of genetic diversity in genome-wide association studies of lipids

Graham SE, Clarke SL, Wu KH, … Christensen H, Brody JA, Feitosa MF, … Thiery J, Bis JC, Nadkarni GN, … Province MA, Psaty BM, Brandslund I, … Deloukas P, Sun YV, Willer CJ. Nature. 2021 Dec;600(7890):675-679. doi: 10.1038/s41586-021-04064-3. Epub 2021 Dec 9. PMID: 34887591.

Epigenome-wide association study of serum urate reveals insights into urate co-regulation and the SLC2A9 locus

Tin A, Schlosser P, Matias-Garcia PR, … Endlich K, Floyd JS, Fraszczyk E, … Prokisch H, Psaty BM, Raitakari OT, … Susztak K, Teumer A, Köttgen A. Nat Commun. 2021 Dec 9;12(1):7173. doi: 10.1038/s41467-021-27198-4. PMID: 34887389.

Two Perspectives: Agricultural Employers and Their Essential Workers

Keifer M. J Agromedicine. 2021 Dec 9. doi: 10.1080/1059924X.2022.2007652. Online ahead of print. PMID: 34850667.

Potential impacts of Washington State's wildfire worker protection rule on construction workers

Zuidema C, Austin E, Cohen MA, Kasner E, Liu L, Busch Isaksen T, Lin KY, Spector J, Seto E. Ann Work Expo Health. 2021 Dec 22:wxab115. doi: 10.1093/annweh/wxab115. Online ahead of print. PMID: 34935028.

Increased labor losses and decreased adaptation potential in a warmer world

Parsons LA, Shindell D, Tigchelaar M, Zhang Y, Spector JT. Nat Commun. 2021 Dec 14;12(1):7286. doi: 10.1038/s41467-021-27328-y. PMID: 34907184

Air pollution and breast cancer: an examination of modification by underlying familial breast cancer risk

Niehoff NM, Terry MB, Bookwalter DB, Kaufman JD, O'Brien KM, Sandler DP, White AJ. Cancer Epidemiol Biomarkers Prev. 2021 Dec 14:cebp.EPI-21-1140-E.2021. doi: 10.1158/1055-9965.EPI-21-1140. Online ahead of print. PMID: 34906967.

Adherence to a MIND-Like Dietary Pattern, Long-Term Exposure to Fine Particulate Matter Air Pollution, and MRI-Based Measures of Brain Volume: The Women's Health Initiative Memory Study-MRI

Chen C, Hayden KM, Kaufman JD, Espeland MA, Whitsel EA, Serre ML, Vizuete W, Orchard TS, Wang X, Chui HC, D'Alton ME, Chen JC, Kahe K. Environ Health Perspect. 2021 Dec;129(12):127008. doi: 10.1289/EHP8036. Epub 2021 Dec 23. PMID: 34939828.

E66.01 (Obesity) and Our Culture of Shame

Hagan S. N Engl J Med. 2021 Dec 16;385(25):2307-2309. doi: 10.1056/NEJMp2111506. Epub 2021 Dec 11. PMID: 34890174.