Highlights of recent faculty research.

Using Area-Level Measures to Account for Social Risk in Health Care Payment

Anna M. Morenz, Joshua M. Liao. Health Affairs Blog. September 16, 2021. DOI: 10.1377/hblog20210913.764162.

Applying behavioral science insights to medical management strategies: The role of validation testing

Zhang IY, Liao JM. Healthc (Amst). 2021 Sep 9;9(4):100582. doi: 10.1016/j.hjdsi.2021.100582. Online ahead of print. PMID: 34509974.

Annual Wellness Visits in the Era of Value-Based Care: National Trends in Use, 2011-2018

Morgan KM, Marcotte LM, Zhou L, Liao JM. J Gen Intern Med. 2021 Sep;36(9):2894-2896. doi: 10.1007/s11606-020-06032-5. Epub 2020 Jul 22. PMID: 32700222. 

ZBTB33 is mutated in clonal hematopoiesis and myelodysplastic syndromes and impacts RNA splicing

Beauchamp EM, Leventhal M, Bernard E, … Anand S, Psaty BM, Desai P, … NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, MacArthur DG, Lek M; Exome Aggregation Consortium, Neuberg DS, Lage K, Carr SA, Hellstrom-Lindberg E, Malcovati L, Papaemmanuil E, Stewart C, Getz G, Bradley RK, Jaiswal S, Ebert BL. Blood Cancer Discov. 2021 Sep;2(5):500-517. doi: 10.1158/2643-3230.BCD-20-0224. Epub 2021 Jul 14. PMID: 34568833.

Whole-genome sequencing in diverse subjects identifies genetic correlates of leukocyte traits: The NHLBI TOPMed program

Mikhaylova AV, McHugh CP, Polfus LM, … Blackwell TW, Brody JA, Broome J, … Perry JA, Psaty BM, Rich SS, … NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Reiner AP, Auer PL. Am J Hum Genet. 2021 Sep 23:S0002-9297(21)00306-2. doi: 10.1016/j.ajhg.2021.08.007. Online ahead of print. PMID: 34582791. 

Whole genome sequence analysis of platelet traits in the NHLBI trans-omics for precision medicine initiative

Little A, Hu Y, Sun Q, … Blackwell TW, Brody JA, Bhan A, … Pankratz N, Psaty BM, Vasan RS, … NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Thornton T, Reiner AP, Johnson AD, Raffield LM. Hum Mol Genet. 2021 Sep 6:ddab252. doi: 10.1093/hmg/ddab252. Online ahead of print. PMID: 34553764.

Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression

Võsa U, Claringbould A, Westra HJ, … Boomsma DI, Psaty BM, Gharib SA, … Gibson G, Esko T, Franke L. Nat Genet. 2021 Sep;53(9):1300-1310. doi: 10.1038/s41588-021-00913-z. Epub 2021 Sep 2. PMID: 34475573.

Long-Term Exposures to Air Pollution and the Risk of Atrial Fibrillation in the Women's Health Initiative Cohort

Hart JE, Hohensee C, Laden F, Holland I, Whitsel EA, Wellenius GA, Winkelmayer WC, Sarto GE, Warsinger Martin L, Manson JE, Greenland P, Kaufman J, Albert C, Perez MV. Environ Health Perspect. 2021 Sep;129(9):97007. doi: 10.1289/EHP7683. Epub 2021 Sep 15. PMID: 34523977. 

Associations of perinatal exposure to PM2.5 with gestational weight gain and offspring birth weight

Liu Z, Szpiro A, Workalemahu T, Young M, Kaufman JD, Enquobahrie D. Environ Res. 2021 Sep 22:112087. doi: 10.1016/j.envres.2021.112087. Online ahead of print. PMID: 34562475. 

Ambient Air Pollution and Long-Term Trajectories of Episodic Memory Decline among Older Women in the WHIMS-ECHO Cohort

Wang X, Younan D, Petkus AJ, Beavers DP, Espeland MA, Chui HC, Resnick SM, Gatz M, Kaufman JD, Wellenius GA, Whitsel EA, Manson JE, Chen JC. Environ Health Perspect. 2021 Sep;129(9):97009. doi: 10.1289/EHP7668. Epub 2021 Sep 13. PMID: 34516296.