Research

This article was updated on 6/11/20.

Grant applications submitted by faculty are bearing fruit for work in research, education, and health services.


Research

Edward Boyko, headshot
Dr. Ed Boyko

Professor Ed Boyko was awarded over $100,000 in funding for his project “The contribution of diabetes to risk of adverse outcomes among veterans with COVID-19” from the VA Clinical Science Research & Development. The nine-month project is designed to quantify the magnitude of the diabetes-related burden of COVID-19 in the VA population and to improve understanding of the mechanisms driving the increased risk of adverse outcomes among veterans with diabetes who develop COVID-19. Dr. Boyko’s co-investigator is Assistant Professor Pandora “Luke” Wander.

 

The National Institutes of Health funded Dr. David Dale’s research on “Gene editing vs. Neutrophil Elastase Inhibitors for Treatment of ELANE-associated Neutropenia.” This three-year project received over $600,000 in grant funding to focus on developing a treatment for certain types of neutropenia.

Additionally, Professor Dale has formed a new industry partnership for UW Medicine with X4 Pharmaceuticals and Syneos Health. Together, they will conduct a Phase 3, randomized, double-blind, placebo-controlled, multicenter study of the drug Mavorixafor in patients with WHIM Syndrome with open-label extension. WHIM (Warts, Hypogammaglobulinemia, Infections, Myelokathexis) Syndrome is a serious, rare genetic disorder caused by a mutation in CXCR4 that causes profound neutropenia, lymphopenia and hypogammaglobulinemia associated with increased rates of bacterial and viral infections.

 

Adelaide McClintock.replacement
Dr. Adelaide McClintock

Dr. Adelaide McClintock has received $4,433 from The Center for Leadership and Innovation in Medical Education (CLIME) small grants program for her 11-month project “Building a Psychologically Safe Learning Environment for our Medical Trainees: Understanding behaviors that create, destroy, and regain psychological safety in clinical teaching environments.” The study’s aim is to gain knowledge around how learners perceive psychological safety as being created, lost, and regained in clinical teaching environments. These findings will allow academic institutions to build faculty development programs and institution-level changes to provide the specific skills and settings that foster psychological safety for learners.

The Center for Leadership and Innovation in Medical Education (CLIME) small grants program supports innovative medical education research and curricular projects across the WWAMI region. Dr. McClintock’s co-investigator is Dr. Joshua Jauregui. Learn more about their project

 

 

Rashmi Sharma, headshot
Dr. Rashmi Sharma

Dr. Rashmi Sharma was awarded $2,500 to use resources available from The UW Institute of Translational Health Sciences to evaluate the association between sociodemographic characteristics and clinical outcomes for patients with COVID-19 and hospitalized within the UW Medicine system. Learn more about her project.

 

In May, the UW Diabetes Research Center granted $100,000 over two years to Dr. Pandora “Luke” Wander for her research “Identifying miRNA-mediated mechanisms driving the protective effects of metformin on beta-cell function.” The goal of this project is to determine whether islet cell miRNAs mediate the effect of metformin on the β-cell, using next-generation miRNA sequencing followed by functional experiments with miRNA inhibitors or mimics in primary mouse islets with replication of key outcomes in isolated human β-cells.


Education

The Substance Abuse and Mental Health Services Administration has funded Assistant Professor Jared Klein’s project “Washington InterProfessional Education for Substance Use Disorders (WIPEout-SUDs)”! UW will receive just shy of $200,000 over two years to create an interprofessional program to address addiction training for students across all UW health science schools. Dr. Klein's GIM program collaborators are Drs. Judith Tsui and Joseph Merrill.

 

Judith Tsui, headshot
Dr. Judith Tsui

Dr. Judith Tsui has received $1.9 million over five years her grant “The UW Medical Student Addiction Research (MedStAR) Program to Address Substance Use and Disorders in Urban and Rural Communities in Five Western States” from the National Institute on Drug Abuse. MedStAR’s goal is to provide opportunities for research and training to medical students considering careers in Addiction Medicine and prepare them to become the next generation of clinicians and scientists to implement and disseminate care for patients with substance use disorders.

 

The UW Addiction Medicine Fellowship Program (headed by Drs. Joseph Merrill, Judith Tsui, and Jared Klein) has received a boost  of $1.3 million over five years from The Health Resources and Services Administration to expand the program from two fellows each year to four. Fellows will train and provide care for underserved populations at Harborview Medical Center, Evergreen Treatment Services, Downtown Public Health Center, and Pioneer Square Clinic/Downtown Programs and will participate in fellow didactics at the VA Puget Sound Health Care SystemActive recruitment is underway.

 

Dr. Linnaea Schuttner received a year of funding from Kaiser Permanente’s CATALyST Scholar Program. The grant will cover research and career development activities, such as travel to scientific meetings, workshops, and conducting a research project.


Services

Genevieve Pagalilauan
Dr. Genevieve Pagalilauan

Associate Professor Genevieve Pagalilauan successfully secured $22,000 from the Pacific Hospital Preservation & Development Authority to expand the UW Health Sciences Mobile Health Van Program. The Program partners with student and local organizations to provide basic preventive health and street medicine services for people experiencing homelessness and housing insecurity.

 

Thanks to the efforts of Dr. Naomi Shike, the Paul G. Allen Foundation awarded $2 million to the UW Medicine Emergency Response Fund for COVID-19 in order to provide two van-based testing sites, one roaming and one home-based at Pioneer Square, to help identify COVID cases among people who are unhoused.