Margaret Isaac, headshot
Associate Professor

Faculty Information


Dr. Isaac is a primary care general internist and palliative medicine physician who practices at Harborview Medical Center. Her clinical interests include caring for marginalized communities, patient-centered care, patient-physician communication, chronic disease management, and holistic care that centers patients' values and goals in their medical decision-making. She is deeply committed to medical education and teaches both pre-clinical and clinical-phase medical students core clinical skills, including communication and history-taking, physical examination, and clinical reasoning.  

Education & Training: 
University of Washington, School of Medicine
Seattle, WA
Internship and Residency in Internal Medicine, Primary Care Track
UCSF San Francisco General Hospital
San Francisco, CA
Fellowship, Hospice and Palliative Medicine
University of California - San Francisco
San Francisco, CA
UW School of Medicine Clinical Sciences Distinguished Teaching Award (2014, 2017, and 2018)
Leonard Tow Humanism in Medicine Award, Gold Humanism Honor Society
Fellow, American College of Physicians
  • Isaac M, Curtis JR. How to respond to an ICU patient asking if they are going to die. Intensive Care Med; 2017 Feb; 43(2): 220-222.
  • Isaac ML, Creutzfeld C. “Sudden Acute Brain Injury.” In Neuropalliative Care: A Guide to Improving the Lives of Patients and Families Affected by Neurologic Disease (Creutzfeld CJ, Kluger BM, Holloway RG, eds.), Springer; 1st edition, 2019. 
  • Molnar A, Isaac ML. “Palliative and End-of-Life Care”; in Refugee Health Care (Annamalai A, ed.); 2nd edition, Springer, pp 181-192, 2019. 
  • Isaac M, Curtis JR. Palliative Care Issues in the ICU, In: UpToDate, Parsons PE, Block SD (ed.), UpToDate, Waltham, MA, 2012, revised 2014, 2016, 2018, 2020.