ProfessorMedicine Section Head, University of Washington Medical CenterRelated Links: Research ProjectsFaculty Information Biography Education & Training: MDUniversity of California, San FranciscoSan Francisco, CA1989–1994 Residency in Internal MedicineUniversity of California, San FranciscoSan Francisco, CA1994–1997 MPHUniversity of WashingtonSeattle, WA2004–2006 MScUniversity of WashingtonSeattle, WA2017 Honors: Dean's Prize for Medical Student Research1992 Martin Memorial Award for Outstanding Second-Year Medicine Resident1996 Weingarten Memorial Award for Outstanding Third-Year Medicine Resident1997 Fellowship, American College of Physicians2003 Alpha Omega Alpha, Honorary Inductee2003 Paul Beeson Award for Excellence in Housestaff Instruction2003 Helen and Phillip Fialkow Scholar2004 Endocrine Society International Award for Excellence in Published Clinical Research2005 Young Andrologist Award2007 Elected Member, American Society of Clinical Investigation2013 Contact Email: jamory@uw.edu Research & Clinical Interests Research Interests: Male contraceptionAndrogens in agingTestosterone deficiencyKlinefelter's SyndromeMale infertility Publications Publications: Amory JK, Wang C, Swerdloff R, Anawalt BD, Matsumoto AM, Bremner WJ, Walker SE, Haberer LJ, Clark RV. The Effect of 5α-Reductase Inhibition with Dutasteride and Finasteride on Semen Parameters and Serum Hormones in Healthy Men. Journal of Clinical Endocrinology and Metabolism 2007; 92:1659–1665. Amory JK, Muller CH, Shimshoni AJ, Isoherranen N, Paik J, Moreb JS, Amory DW, Evanoff R, Goldstein AS, Griswold MD. Suppression of spermatogenesis by bisdichloroacetyldiamines is mediated by inhibition of testicular retinoic acid biosynthesis. Journal of Andrology 2011; 32(1):111–119. PMCID: PMC3370679. Nya-Ngatchou JJ, Arnold SLM, Walsh TJ, Muller CH, Page ST, Isoherranen N, Amory JK. Intratesticular 13-cis Retinoic Acid is Reduced in Men with Abnormal Semen Analyses. Andrology 2013 March; 1: 325–331. PMCID: PMC3578657. Amory JK, Arnold S, Walsh T, Lardone MC, Piottante A, Ebensperger MD, Isoherraenen N, Muller CH, Castro A. Levels of the Retinoic Acid Synthesizing Enzyme ALDH1A2 are Lower in Testicular Tissue from Men with Infertility. Fertility and Sterility 2014 Apr;101(4):960–966. PMCID:PMC3972330. Paik J, Haenisch M, Muller CH, Goldstein AS, Arnold S, Isoherranen H, Brabb T, Treuting PM, Amory JK. Inhibition of Retinoic Acid Biosynthesis by WIN 18,446 Markedly Suppresses Spermatogenesis and alters Retinoid Metabolism in Mice. Journal of Biological Chemistry 2014 May 23;289(21):15104–17. PMCID: PMC4031560. Amory JK, Ostrowski KA, Gannon JR, Berkseth K, Stevison F, Isoherranen N, Muller CH, Walsh T. Isotretinoin administration improves sperm production in some men with infertility from oligoasthenozoospermia: A Pilot Study. Andrology 2017 5:1115–1123. Chen Y, Zhu J, Ho Hong K, Georg G, Goldstein AS, Amory JK, Schonbrunn E. Structural basis of ALDH1A2 inhibition by irreversible and reversible small molecule inhibitors. ACS Chemical Biology 2018 Mar 16;13(3):582–590.
